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LF, Lactoferrin lactotransferrin SARS-CoV, acute respiratory syndrome coronavirus LRP-1/CD91, LDL receptor-linked protein-1 TLR2 and 4, Toll-like receptor 2 and four CXCR4, cytokine receptor four GAG, glycosaminoglycan AP-1, activator protein one NF-κB, NF-kappa beta IRF, Interferon regulatory component MAPK, Mitogen-activated protein kinase HSPG, Heparan sulfate proteoglycans ACE2, Angiotensin-converting enzyme two IL, Interleukin G-CSF, Granulocyte colony-stimulating component GM-CSF, Granulocyte-Macrophage Colony Stimulating Component IFN, Interferon TNFα, Tumor necrosis component alpha IP10, Interferon gamma-induced protein ten MCP1, Monocyte Chemoattractant Protein-1 (MIP1) A and B, Macrophage inflammatory protein one (A and B) LMWH, Low molecular body weight heparin vWF, von Willebrand Component PAD4, protein arginine deiminase 4 NETS, Neutrophil extracellular traps. These indicators are involved with a cytokine storm (166, 167) manifesting elevated serum concentrations of interleukin (IL) IL-1β, IL-2, IL-7, IL-8, IL-9, IL-10, IL-17, granulocyte colony-stimulating component (G-CSF), Granulocyte-Macrophage Colony Stimulating Component (GM-CSF), interferon (IFN)γ, tumor necrosis component (TNF)α, Interferon gamma-induced protein ten (IP10), Monocyte Chemoattractant Protein-1 (MCP1), macrophage inflammatory protein 1(MIP1)A and MIP1B (168). IL-22, in collaboration with IL-17 and TNFα, induces antimicrobial peptides in the mucosal organs. 8. Hondermarck H, Bartlett NW, Nurcombe V. The purpose of development component receptors in viral infections: an opportunity for drug repurposing towards rising viral health conditions this kind of as COVID-19? FASEB Bioadv

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