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Révision datée du 11 juin 2023 à 16:09 par SommerBarden (discussion | contributions) (Page créée avec « <br>There has been speculation that he was assassinated by the Nazis to conceal the connection but there is no evidence for it. It is not understood how the activated RISC… »)
There has been speculation that he was assassinated by the Nazis to conceal the connection but there is no evidence for it. It is not understood how the activated RISC advanced locates complementary mRNAs in the cell. In a lot of organisms, such as people, miRNAs are connected to the formation of tumors and dysregulation of the cell cycle. The results of miRNA dysregulation of gene expression also appear to be to be significant in neuropsychiatric issues, such as schizophrenia, bipolar disorder, key melancholy, Parkinson's disorder, Alzheimer's condition and autism spectrum problems. A miRNA is expressed from a substantially more time RNA-coding gene as a most important transcript recognized as a pri-miRNA which is processed, in the cell nucleus, to a 70-nucleotide stem-loop composition called a pre-miRNA by the microprocessor sophisticated. The initiating dsRNA can also be endogenous (originating in the cell), as in pre-microRNAs expressed from RNA-coding genes in the genome. Organisms fluctuate in their means to take up foreign dsRNA and use it in the RNAi pathway. Thus, the two dsRNA pathways, exogenous and endogenous, converge at the RISC
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